Cytochrome c oxidase subunit 6a1
WebMechanistically, gefitinib selectively degrades the important anti-apoptosis factor COX6A1 (cytochrome c oxidase subunit 6A1) in the autophagy-lysosome pathway. The … WebLOC128062396 cytochrome c oxidase subunit 6A1, mitochondrial [ (takin)] Gene ID: 128062396, updated on 28-Feb-2024. Summary Other designations. cytochrome c oxidase subunit 6A1, mitochondrial ...
Cytochrome c oxidase subunit 6a1
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WebOct 28, 2024 · PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1). Autophagy. 2024; 14: 1-17. 4. He QJ*. HMGB1 represses the anti-cancer activity of sunitinib by governing TP53 autophagic degradation via its nucleus-to-cytoplasm transport. Autophagy. WebCytochrome c oxidase (CcO) is a large integral membrane protein which is encoded in the mitochondrial genome. It is a terminal oxidase of the mitochondrial electron transport chain, and it is expressed in the mitochondrial inner membrane. Assembly of the active oxidase complex is dependent on the insertion of three Cu ions, along with two heme ...
WebAug 4, 2004 · Cytochrome c oxidase (COX) is a multimeric enzyme consisting of 13 subunits that are encoded in both mitochondrial and nuclear genomes. We analyzed the promoter of the rat gene encoding the liver isoform of COX subunit VIa. Using transiently transfected primary neuronal cultures as a model system, we found that the basal … WebThe cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.
Webcytochrome c oxidase subunit VIa GeneRIFs: Gene References Into Functions Point mutations are introduced into subunit I of a mutant mitochondrial yeast strain with a histidine tag on the nuclear-encoded Cox13 subunit shows mechanistic effects of mutations on respiratory growth. Cytochrome c oxidase subunit 6A1, mitochondrial is a protein that in humans is encoded by the COX6A1 gene. Cytochrome c oxidase 6A1 is a subunit of the cytochrome c oxidase complex, also known as Complex IV, the last enzyme in the mitochondrial electron transport chain. A mutation of the … See more The COX6A1 gene, located on the q arm of chromosome 12 in position 24.2, contains 3 exons and is 2,653 base pairs in length. The COX6A1 protein weighs 12 kDa and is composed of 109 amino acids. The protein is a … See more Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton … See more • Mass spectrometry characterization of COX6A1 at COPaKB • Human COX6A1 genome location and COX6A1 gene details page in the UCSC Genome Browser. • Overview of all the structural information available in the PDB for UniProt: P12074 (Cytochrome c … See more A mutation leading to a 5 base pair deletion in the COX6A1 gene is associated with Charcot-Marie-Tooth disease (CMT). CMT is the most common inherited neuropathy and can result from … See more • Hochstrasser DF, Frutiger S, Paquet N, Bairoch A, Ravier F, Pasquali C, Sanchez JC, Tissot JD, Bjellqvist B, Vargas R (Dec 1992). "Human … See more
Webcytochrome c oxidase subunit 6A1 Symbol cox6a1 Nomenclature History Previous Names ns:zf-e250 zgc:103782 Type protein_coding_gene Location Chr: 8 Mapping Details/Browsers Description Predicted to enable enzyme regulator activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen.
Web8 rows · Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of ... ian ginnard weddingWebCytochrome c oxidase, the terminal enzyme of the respiratory chains of mitochondria and aerobic bacteria, catalyzes electron transfer from cytochrome c to molecular oxygen, reducing the latter to water. Electron transfer is coupled to proton translocation across the membrane, resulting in a proton and charge gradient that is then employed by ... moms who think dinner recipesWebDec 8, 2024 · Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. … moms who beat the systemWebEach Cytochrome C Oxidase subunit 6c Antibody is fully covered by our Guarantee+, to give you complete peace of mind and the support when you need it. Our Cytochrome C … moms whole foods new castle paWebHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality changes and dementia. ian gladwin penistoneWebNational Center for Biotechnology Information ian glanister deathWebUniProt website fallback message If you are not seeing anything on this page, it might be for multiple reasons: You might have JavaScript disabled: make sure to ... moms who retreat